The Top Performing IPO Stock Of 2021


2021 was the busiest year for deals since 2000, with a record-breaking IPO rush of 1,035 listings in the US, with the biotech and healthcare sectors leading the way, accounting for 36% of all IPO activity.

While most investors are busy reviewing stocks in their current portfolio, it may come as a surprise which company came in first for stock return. Although it is currently not a household name, any savvy investor should definitely keep this stock on their radar: Regencell Bioscience (NASDAQ:RGC). RGC is the top performing stock of all 2021 IPOs according to As of August 1, 2022, RGC is still ranked #1 with a 237% return above its IPO price of $9.50.

A June 2022 article mentioned that RGC’s total cumulative short volume is over 19 million shares. While the stock has suffered from short sellers’ attacks since its listing, RGC has performed well. RGC has approximately 2.6 million tradable ordinary shares in the market and has maintained a low float as the founder and CEO has repeatedly purchased RGC ordinary shares from the open market. 

RGC’s Solid Foundation

As mentioned above, RGC is closely held by the CEO who owns over 81% of the company. He has used $5.9 million of his personal funds to purchase RGC shares from the open market since its IPO.

His consistent share purchases convey his confidence, commitment and conviction in the company and is putting his money where his mouth is. There are few companies that  have the CEO owning this much of the business. The company’s entire management team has also extended the lock-up period of their share options, which shows they are collectively committed to their goal and mission, which is to save and improve lives.

Comparison to 2022 IPO Top Performer

A recent stock that has gone to the moon since its mid-July 2022 IPO is a company founded by Mr. Li Ka-Shing’s Cheung Kong Group and Hutchison Whampoa in 2003, AMTD Digital (NYSE:HKD). HKD’s IPO price was $7.80 and has gained over 9,000% since, closing at $742.00 on August 1, 2022. Although RGC is the #1 performer of 2021 IPOs, this pales in comparison with the current performance of HKD. Astute traders who have an eye for forensic analysis in companies with low float and outsized short interest are indeed very happy.

RGC was also listed in mid-July and is based in Hong Kong. In fact, there are a few similarities between the two companies. Both RGC and HKD are founded by individuals (Mr. Au for RGC and Mr. Li for HKD), who believe in philanthropy and giving back to society. HKD’s upward trajectory which has delivered an incredible 90 times bagger in a short amount of time has also attracted many short positions against the company. Below is a table outlining the key metrics:




IPO Date 

July 16, 2021

July 15, 2022

IPO Price (USD)



As of August 1, 2022



Share performance since IPO (multiples)



IPO Ranking 2021



IPO Ranking 2022


Principal Office

Hong Kong

Hong Kong

Major shareholder (%)



Daily short volume ratio (1 month) (%) 

(refer to charts below)



Daily short volume ratio (1 year) – Highest (%)

(refer to charts below)



Daily short volume (%) refers to the number of shares that have been shorted as compared to the total daily volume traded.

Only time will tell if RGC achieves similar heights, but the similarities seem interesting. 

RGC and HKD Comparison Chart

RGC’s Stock Chart Since IPO:


RGC’s Daily Short Volume Ratio (1 month) (7):


RGC’s Daily Short Volume Ratio (1 year) (7):


HKD’s Stock Chart Since IPO:


HKD’s Daily Short Volume Ratio (1 month) (8):




Source from: Benzinga